FlowCytoNews
Flow cytometry, gated weekly.
SPECIAL EDITION · THANK YOU · OCT 21, 2026
Thank you to everyone who subscribed recently. FlowCytoNews is written for the people who run the instruments and use the data: core staff, clinical cytometrists, immunologists, and flow scientists at biopharma companies, CROs and CDMOs. This edition explains what you'll get from here on and gives you a short sample of each part. Tell us what we missed — hit reply.
■ What lands in your inbox
Three editions a week, each with a single job:
Day | Edition | What's in it |
|---|---|---|
Monday | The Literature | The cytometry papers and preprints from the last two weeks: who did the work, where, and the number that matters from each one. New OMIPs always run. |
Wednesday | On the Calendar | Meetings, courses, webinars and deadlines for the next eight weeks, each linked to the host's own page, plus what came out of meetings that just ended. |
Friday | Industry Moves | What instrument, reagent, CRO, CDMO and cell-therapy companies did that week, with the primary source linked, plus open flow jobs. |
Every edition ends with Bench Notes: one practical, cited how-to tied to that edition's news. Now and then we run a special edition on a single topic, like our nanoflow guide on calibrating EV measurements.
The house rules: every fact links to its source, and opinion stays in the "Why it matters" line so you can tell the two apart. We cover competing vendors the same way and flag industry co-authors on papers.
■ A sample of each
A taste of each edition, one item apiece.
Monday · The Literature
Seumetry brings Seurat-style analysis to flow and mass cytometry
Malte Borggrewe, Stefan Bonn and Madeleine Bunders (University Medical Center Hamburg-Eppendorf and the Leibniz Institute of Virology, Hamburg) published Seumetry, an R toolkit that combines cytometry-specific analysis methods with Seurat, a tool built for single-cell RNA-seq data. It covers quality control, visualization, and differential abundance and protein expression analysis. They tested it on an in-house dataset of human intestinal immune cells and on public datasets, and report that its results agree with manual gating. No industry co-authors.
▪ Bioinformatics · Oct 13 · 10.1093/bioinformatics/btag730
Why it matters: Cores that already support single-cell sequencing users can hand them cytometry data in a framework they know. Before you switch pipelines, check it against your own manual gates on one of your datasets.
Wednesday · On the Calendar
CYTO 2027 abstracts are due Dec 6
ISAC's CYTO 2027 runs Jun 5–9, 2027 in Helsinki. The abstract site was scheduled to open Oct 19, and the deadline is Dec 6. Student and SRL Junior Travel Awards require an abstract, and the application materials go in through the abstract site by the same deadline.
▪ ISAC · CYTO abstracts · travel awards · future meetings
Friday · Industry Moves
Danaher and Thermo Fisher both grew Q3 sales; neither broke out flow
Danaher reported Q3 revenue up 8.5% to $6.6B, with core revenue up 3.0%. Life Sciences core sales grew 4.5%, and Danaher raised its full-year adjusted EPS guidance to $8.57–8.62. Thermo Fisher reported revenue up 9% to $12.14B, with 6% organic growth. Its Life Sciences Solutions segment rose to $2,719M from $2,588M, and Analytical Instruments to $2,002M from $1,893M. Both reported on Oct 21. Neither release mentions flow cytometry.
▪ Danaher and Thermo Fisher · Oct 21 · Danaher release (SEC) · Thermo Fisher release (SEC)
Who's hiring
Friday editions also list open flow cytometry jobs. Here are eight we found open on Oct 21:
Company | Role | Location · pay |
|---|---|---|
Beam Therapeutics | Cambridge, MA · $95–115K | |
Gilead Sciences | Foster City, CA · $117,895–152,570 | |
Frontage Laboratories | Exton, PA · pay not shown | |
KCAS Bio | Philadelphia, PA · pay not shown | |
Mayo Clinic | Rochester, MN · $67,454–101,213 | |
Mount Sinai Medical Center | Miami Beach, FL · base pay not shown; $25K sign-on bonus | |
Regional Cancer Care Associates | Little Silver, NJ · $31.03–60.00/hr | |
Thermo Fisher Scientific | Cambridge, MA · $84,000–124,925 |
▪ Postings via ZipRecruiter; each was open when checked on Oct 21. Pay is shown only where the posting lists it.
Every edition · Bench Notes
Track your cytometer's spillover spreading matrix as a QC check
Nguyen and colleagues at the NIH Vaccine Research Center built a spillover spreading matrix (SSM) from single-stained controls. It measures how much a bright signal in one color spreads into other detectors and cuts sensitivity there. On their instruments the SSM was reproducible, with non-trivial values varying by a CV under 30% over two months. It was also comparable between similarly configured instruments, and differences between instruments exposed underperforming detectors (Cytometry A 2013, 10.1002/cyto.a.22251). To use it:
Calculate an SSM from your single-stained controls, and repeat it on a regular schedule.
Compare each new SSM with your earlier ones, and with SSMs from similarly configured instruments in your facility.
Investigate any detector whose values have moved away from its history or from its sister instruments. The authors found that differences like these revealed underperforming detectors.
■ Tell us what you want
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I work full time and have a family, so FlowCytoNews is AI-generated. I set it up with a skill that requires every fact to cite its source and link to it, keeps opinion confined to the "Why it matters" lines, and forbids making anything up.
These are the connectors it uses:
PubMed, for papers and their abstracts
bioRxiv, for preprints
Crossref, to check every DOI, journal and publication date
JobDataLake, for flow cytometry job listings
Web search and fetch, to open the original source for everything else: company press releases and SEC filings, society and meeting pages, and vendor event pages
I review every edition, but mistakes can still get through. If you spot one, tell me and the correction will run at the top of the next edition.
FlowCytoNews is for informational and entertainment purposes only. It is not scientific, medical, clinical, legal or investment advice. Check the original source before you rely on anything here.
Please always reply with feedback. That's how we make it better.
Thanks again for reading. See you Monday.
— Flow Novice